SCHEMBL30905728

SCHEMBL30905728

N#Cc1cccc(-c2ccc(=O)n(Cc3cccc(-c4ncc(N5CCN(CC6CCN(c7ccc(NC8CCC(=O)NC8=O)cc7F)CC6)CC5)cn4)c3)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 15/20 0.50
▸ NQO2 P16083 1/20 0.50
▸ CRBN Q96SW2 4/20 0.37
▸ DDB1 Q16531 3/20 0.37
▸ ADRA1D P25100 1/20 0.37
▸ ADRA1A P35348 1/20 0.37
▸ ADRA1B P35368 1/20 0.37
▸ IKZF3 Q9UKT9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30979630 0.96 MET (0.49) METNQO2CRBNDDB1ADRA1D
SCHEMBL30905745 0.92 MET (0.51) METNQO2CRBNDDB1ADRA1D
SCHEMBL31690314 0.90 MET (0.63) METNQO2
SCHEMBL30979625 0.90 MET (0.62) METNQO2CRBNDDB1
SCHEMBL30905762 0.90 MET (0.54) METNQO2CRBNDDB1ADRA1D
SCHEMBL30905718 0.90 MET (0.61) METNQO2
SCHEMBL30905755 0.89 MET (0.54) METNQO2CRBNDDB1ADRA1D
SCHEMBL30905793 0.89 MET (0.59) METNQO2
SCHEMBL30905742 0.87 MET (0.56) METNQO2CRBNDDB1ADRA1D
SCHEMBL31690381 0.85 MET (0.57) METNQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624466-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP claimed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP claimed
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO claimed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO claimed
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO disclosed
WO-2024112119-A1 DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO disclosed
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