SCHEMBL30979625

SCHEMBL30979625

N#Cc1cccc(-c2ccc(=O)n(Cc3cccc(-c4ncc(OCCN5CCN(c6ccc(NC7CCC(=O)NC7=O)cc6F)CC5)cn4)c3)n2)c1

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MET P08581 18/20 0.62
▸ NQO2 P16083 1/20 0.56
▸ DDB1 Q16531 1/20 0.39
▸ CRBN Q96SW2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30905718 0.95 MET (0.61) METNQO2
SCHEMBL31690314 0.93 MET (0.63) METNQO2
SCHEMBL30905745 0.93 MET (0.51) METNQO2DDB1CRBN
SCHEMBL30905742 0.91 MET (0.56) METNQO2DDB1CRBN
SCHEMBL30905728 0.90 MET (0.50) METNQO2DDB1CRBN
SCHEMBL30905793 0.89 MET (0.59) METNQO2
SCHEMBL27401404 0.88 MET (0.54) METNQO2
SCHEMBL30979620 0.88 MET (0.54) METNQO2
SCHEMBL30979630 0.88 MET (0.49) METNQO2DDB1CRBN
SCHEMBL30905755 0.88 MET (0.54) METNQO2DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO claimed
EP-4624472-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME Innocure Therapeutics, Inc. (KR) 2025-10-01 — — EP disclosed
WO-2024112120-A1 DEGRADER INCLUDING NOVEL C-MET PROTEIN LIGAND AND PHARMACEUTICAL COMPOSITION INCLUDING SAME 주식회사 이노큐어테라퓨틱스 2024-05-30 — — WO disclosed
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