Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979625 | 0.93 | MET (0.62) | METNQO2CRBNDDB1 | |
| SCHEMBL30905728 | 0.92 | MET (0.50) | METNQO2CRBNDDB1ADRA1D | |
| SCHEMBL30905718 | 0.90 | MET (0.61) | METNQO2 | |
| SCHEMBL30979630 | 0.90 | MET (0.49) | METNQO2CRBNDDB1ADRA1D | |
| SCHEMBL31690314 | 0.90 | MET (0.63) | METNQO2 | |
| SCHEMBL30905742 | 0.88 | MET (0.56) | METNQO2CRBNDDB1ADRA1D | |
| SCHEMBL30905793 | 0.86 | MET (0.59) | METNQO2 | |
| SCHEMBL30905755 | 0.85 | MET (0.54) | METNQO2CRBNDDB1ADRA1D | |
| SCHEMBL30979620 | 0.85 | MET (0.54) | METNQO2 | |
| SCHEMBL27401404 | 0.85 | MET (0.54) | METNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | claimed |
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |