SCHEMBL30906003

SCHEMBL30906003

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 2/20 0.57
MC4R P32245 1/20 0.55
APLNR P35414 1/20 0.53
RAMP3 O60896 1/20 0.53
CALCR P30988 1/20 0.53
OPRD1 P41143 1/20 0.52
NTSR2 O95665 2/20 0.52
NTSR1 P30989 2/20 0.52
SORT1 Q99523 2/20 0.52
OPRM1 P35372 6/20 0.52
OPRK1 P41145 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30906000 0.95 C5AR1 (0.58) C5AR1MC4RAPLNRRAMP3CALCR
SCHEMBL30906005 0.91 NTSR1 (0.60) OPRD1NTSR2NTSR1SORT1
SCHEMBL30906006 0.89 NTSR1 (0.57) C5AR1NTSR2NTSR1SORT1
SCHEMBL14479419 0.89 OPRM1 (0.59) OPRM1OPRK1
SCHEMBL14479406 0.89 KDM1A (0.59) OPRM1OPRK1
SCHEMBL30903267 0.88 NPY2R (0.59) C5AR1CALCR
SCHEMBL29607152 0.88 APLNR (0.55) C5AR1MC4RAPLNROPRM1OPRK1
SCHEMBL29608111 0.88 APLNR (0.55) C5AR1MC4RAPLNROPRM1OPRK1
SCHEMBL17166120 0.88 KDM1A (0.58) C5AR1OPRM1OPRK1
SCHEMBL14479426 0.88 KDM1A (0.58) C5AR1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4622672-A1 AMYLIN ANALOGUES IP2IPO Innovations Limited (GB) 2025-10-01 EP disclosed
WO-2024110763-A1 AMYLIN ANALOGUES IP2IPO INNOVATIONS LIMITED (GB) 2024-05-30 WO disclosed