SCHEMBL30906362

CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O

nearest known ligand 0.66

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	2/20	0.57

▸	OPRM1	P35372	2/20	0.56

▸	OPRD1	P41143	2/20	0.56

▸	OPRK1	P41145	2/20	0.56

▸	CALCR	P30988	3/20	0.56

▸	TFPI	P10646	4/20	0.56

▸	NPY2R	P49146	5/20	0.55

▸	NPY4R	P50391	5/20	0.55

▸	NPY5R	Q15761	5/20	0.55

▸	NPY1R	P25929	3/20	0.55

▸	F2	P00734	1/20	0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30906344	0.98	KEAP1 (0.59)	KEAP1CALCRTFPINPY2RNPY4R
SCHEMBL30906484	0.96	TFPI (0.59)	OPRM1OPRD1OPRK1CALCRTFPI
SCHEMBL30906472	0.91	EP300 (0.54)	OPRD1CALCRNPY2RNPY4RNPY5R
SCHEMBL29656041	0.90	OPRD1 (0.61)	KEAP1OPRM1OPRD1OPRK1CALCR
SCHEMBL30495652	0.90	CALCR (0.58)	OPRM1OPRD1OPRK1CALCRNPY2R
SCHEMBL31688332	0.90	OPRM1 (0.61)	KEAP1OPRM1OPRD1OPRK1CALCR
SCHEMBL29531542	0.90	NPY2R (0.63)	CALCRTFPINPY2RNPY4RNPY5R
SCHEMBL30262116	0.89	F2 (0.62)	OPRD1CALCRTFPINPY2RNPY4R
SCHEMBL30432023	0.89	OPRM1 (0.58)	OPRM1OPRD1OPRK1CALCRTFPI
SCHEMBL31000910	0.89	TFPI (0.62)	OPRM1OPRD1OPRK1CALCRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4598964-A2	ANTI-IGE ANTIBODIES	Abwiz Bio, Inc. (US)	2025-08-13	—	—	EP	disclosed
US-20240182599-A1	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC.	2024-06-06	—	—	US	disclosed
WO-2024076785-A2	ANTI-IGE ANTIBODIES	ABWIZ BIO, INC. (US)	2024-04-11	—	—	WO	disclosed