Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486053 | 0.76 | HCRTR1 (0.37) | MAPTHCRTR1HCRTR2PDE2APOLB | |
| SCHEMBL16804955 | 0.75 | DHFR (0.38) | MAPTHCRTR1HCRTR2PDE2A | |
| SCHEMBL30907645 | 0.75 | HCRTR1 (0.34) | MAPTHCRTR1HCRTR2PDE2A | |
| SCHEMBL15142441 | 0.74 | AXL (0.35) | MEN1MAPTKMT2ACSNK2A1HTT | |
| SCHEMBL153228 | 0.72 | CHEK1 (0.41) | HTT | |
| SCHEMBL25826358 | 0.72 | MEN1 (0.44) | MEN1MAPTKMT2A | |
| SCHEMBL30736092 | 0.72 | MEN1 (0.44) | MEN1MAPTKMT2A | |
| SCHEMBL19502144 | 0.72 | RECQL (0.33) | HTTPOLB | |
| SCHEMBL16783064 | 0.72 | ALDH1A1 (0.33) | MAPTHCRTR1HCRTR2PDE2A | |
| SCHEMBL27862145 | 0.70 | HCRTR1 (0.34) | HCRTR1HCRTR2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |