Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907519 | 0.81 | — | — | |
| SCHEMBL3675774 | 0.77 | APLNR (0.36) | APLNR | |
| SCHEMBL30907345 | 0.72 | NOS2 (0.42) | — | |
| SCHEMBL27141629 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL27141626 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL30992834 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL30780284 | 0.72 | CA2 (0.34) | — | |
| SCHEMBL31658840 | 0.71 | AAK1 (0.31) | — | |
| SCHEMBL14244530 | 0.70 | APLNR (0.31) | APLNR | |
| SCHEMBL20578340 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |