Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907125 | 0.91 | ABL1 (0.42) | ABL1AGPAT2PDGFRBPDGFRA | |
| SCHEMBL30907424 | 0.91 | ABL1 (0.42) | ABL1AGPAT2PDGFRBPDGFRA | |
| SCHEMBL30907451 | 0.86 | ABL1 (0.39) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30907372 | 0.84 | ABL1 (0.42) | ABL1 | |
| SCHEMBL30907414 | 0.84 | GABRA1 (0.36) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30907111 | 0.84 | ABL1 (0.43) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30907661 | 0.83 | GABRA1 (0.34) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30907381 | 0.82 | ABL1 (0.32) | ABL1PDGFRBPDGFRA | |
| SCHEMBL30907510 | 0.81 | GABRA1 (0.33) | ABL1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30907570 | 0.81 | DHFR (0.37) | ABL1GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |