Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907168 | 0.91 | DCTPP1 (0.34) | ABL1MCHR1TNIKACP1DCTPP1 | |
| SCHEMBL30907176 | 0.82 | MKNK2 (0.40) | ABL1MCHR1 | |
| SCHEMBL30907612 | 0.82 | KDM1A (0.39) | FGFR1LCKKITSRCABL1 | |
| SCHEMBL30907192 | 0.81 | ABL1 (0.44) | ABL1 | |
| SCHEMBL30907201 | 0.76 | AURKA (0.37) | DCTPP1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL30907364 | 0.72 | KDM1A (0.39) | MCHR1ACP1DCTPP1MEN1KMT2A | |
| SCHEMBL30907575 | 0.65 | ABL1 (0.45) | ABL1 | |
| SCHEMBL30236507 | 0.64 | ALDH1A1 (0.39) | LCKKITSRCDCTPP1PDGFRB | |
| SCHEMBL30236143 | 0.61 | GRM5 (0.37) | KCNH2LCKKITSRCABL1 | |
| SCHEMBL30236197 | 0.61 | CLK4 (0.44) | ABL1KMT2AL3MBTL1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |