Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30907168 | 0.76 | DCTPP1 (0.34) | DCTPP1 | |
| SCHEMBL30907183 | 0.76 | HDAC1 (0.47) | DCTPP1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL30907376 | 0.76 | FGFR1 (0.35) | GAADCTPP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20489451 | 0.65 | KMT2A (0.52) | GAAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL27172033 | 0.63 | KDM4E (0.56) | GAADCTPP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5459236 | 0.61 | ALDH1A1 (0.56) | KMT2AKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL12821489 | 0.61 | LMNA (0.49) | GAADCTPP1NPBWR1KDM4EALDH1A1 | |
| SCHEMBL21383569 | 0.60 | HDAC1 (0.53) | GAASIGMAR1L3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL15242958 | 0.60 | KDM4E (0.50) | GAASIGMAR1DCTPP1MEN1KMT2A | |
| SCHEMBL27807343 | 0.60 | NPBWR1 (0.51) | SIGMAR1NPBWR1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097953-A1 | NAPHTHYRIDINE COMPOUNDS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2024-05-10 | — | — | WO | disclosed |