Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908664 | 0.82 | MEN1 (0.54) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL30111052 | 0.82 | MEN1 (0.54) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL8327255 | 0.82 | MEN1 (0.54) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL30659388 | 0.80 | APEX1 (0.48) | MEN1KMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9087640 | 0.79 | TSHR (0.51) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL5376331 | 0.76 | MEN1 (0.65) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL31444015 | 0.75 | CA12 (0.43) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL4767130 | 0.75 | ALDH1A1 (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31120599 | 0.75 | MEN1 (0.49) | MEN1KMT2AEGFRGSTP1GSTM2 | |
| SCHEMBL543367 | 0.74 | ALDH1A1 (0.54) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024206347-A1 | FUSED THIADIAZINE DIOXIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |