Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908240 | 0.93 | GSK3B (0.37) | IRAK4GSK3BDYRK1AMAPK14SCN9A | |
| SCHEMBL30908217 | 0.92 | GSK3B (0.37) | IRAK4GSK3BDYRK1AMAPK14SCN9A | |
| SCHEMBL30908165 | 0.92 | GSK3B (0.36) | IRAK4GSK3BDYRK1AMAPK14SCN9A | |
| SCHEMBL30908596 | 0.88 | GSK3B (0.39) | IRAK4GSK3BDYRK1AMAPK14SCN9A | |
| SCHEMBL30908400 | 0.86 | STING1 (0.40) | IRAK4GSK3BDYRK1ASTING1 | |
| SCHEMBL30908563 | 0.86 | GSK3B (0.36) | IRAK4GSK3BDYRK1AMAPK14SCN9A | |
| SCHEMBL30908147 | 0.86 | GSK3B (0.33) | IRAK4GSK3BDYRK1A | |
| SCHEMBL30908442 | 0.82 | AURKA (0.37) | GRM2SCN9A | |
| SCHEMBL30908587 | 0.81 | HTR6 (0.37) | HTR6 | |
| SCHEMBL30908271 | 0.79 | PTPN1 (0.36) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |