Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | MTTP | P55157 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908271 | 0.93 | PTPN1 (0.36) | SCN9ATOP2ATOP2BNPC1RAB9A | |
| SCHEMBL30908483 | 0.91 | TSPO (0.39) | SCN9AHDAC1TOP2ATOP2BNPC1 | |
| SCHEMBL30908503 | 0.86 | NPC1 (0.35) | SCN9AHDAC1TOP2ATOP2BNPC1 | |
| SCHEMBL30908391 | 0.86 | TOP2A (0.35) | GRM2SCN9AHDAC1TOP2ATOP2B | |
| SCHEMBL30908405 | 0.84 | HDAC1 (0.35) | GRM2SCN9AHDAC1TOP2ATOP2B | |
| SCHEMBL30908418 | 0.82 | SCN9A (0.41) | SCN9ATOP2ATOP2BAKT1ALDH1A1 | |
| SCHEMBL30908423 | 0.82 | SCN9A (0.41) | SCN9ATOP2ATOP2BAKT1ALDH1A1 | |
| SCHEMBL30908221 | 0.82 | IRAK4 (0.42) | GRM2SCN9A | |
| SCHEMBL30908158 | 0.82 | METAP1 (0.39) | SCN9AHDAC1TOP2ATOP2BAKT1 | |
| SCHEMBL30908640 | 0.79 | NOS1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |