Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544393 | 0.84 | GAA (0.60) | KMT2AKCNMA1MAPK1RAB9AHTT | |
| SCHEMBL30908187 | 0.81 | TSHR (0.59) | KMT2AKCNMA1POLBMAPK1RAB9A | |
| SCHEMBL14880185 | 0.77 | CYP2C19 (0.67) | TDP1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6378760 | 0.76 | HTT (0.66) | TDP1ALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL30908178 | 0.76 | USP36 (0.45) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24465550 | 0.76 | MAPK1 (0.54) | KMT2APOLBMAPK1ALDH1A1KDM4E | |
| SCHEMBL17801307 | 0.76 | KCNMA1 (0.64) | TDP1KMT2AKCNMA1MAPK1ALDH1A1 | |
| SCHEMBL23330651 | 0.76 | HTT (0.58) | KMT2AKCNMA1MAPK1ALDH1A1RAB9A | |
| SCHEMBL18086522 | 0.76 | RAB9A (0.67) | TDP1KCNMA1POLBALDH1A1KDM4E | |
| SCHEMBL15291342 | 0.75 | SMN1; SMN2 (0.70) | TDP1POLBALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |