Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP36 | Q9P275 | 5/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 3/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30908501 | 0.82 | DDR1 (0.41) | USP36DDR1BRAFCSF1RPOLB | |
| SCHEMBL30908468 | 0.81 | JUN (0.45) | JUNNFKB1NFKB2RELACSF1R | |
| SCHEMBL30908239 | 0.76 | TDP1 (0.59) | POLBNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL31013252 | 0.76 | KDR (0.54) | BRAFJUNNFKB1NFKB2RELA | |
| SCHEMBL30908187 | 0.76 | TSHR (0.59) | BRAFCSF1RNNMTPOLBGAA | |
| SCHEMBL22583216 | 0.73 | GPR35 (0.47) | JUNNFKB1NFKB2RELAPOLB | |
| SCHEMBL22715430 | 0.72 | GPR35 (0.44) | POLBNPC1RAB9AKMT2A | |
| SCHEMBL2265349 | 0.72 | ALDH1A1 (0.51) | JUNNFKB1NFKB2RELAGAA | |
| SCHEMBL3942796 | 0.72 | GAA (0.63) | BRAFCSF1RKCNQ3KCNQ2KCNE1 | |
| SCHEMBL3933821 | 0.72 | KCNQ3 (0.64) | BRAFCSF1RKCNQ3KCNQ2KCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |