Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487373 | 1.00 | HCAR2 (0.47) | HCAR2POLBNAPRTTTRTSHR | |
| SCHEMBL20271233 | 0.82 | NNMT (0.41) | PLAULMNA | |
| SCHEMBL29365646 | 0.79 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL487368 | 0.79 | HCAR2 (0.50) | HCAR2POLBNAPRTTTRMGAM | |
| SCHEMBL232290 | 0.79 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL30792836 | 0.79 | HCAR2 (0.50) | HCAR2POLBNAPRTTTRMGAM | |
| SCHEMBL24213965 | 0.78 | MAPK1 (0.46) | POLBALDH1A1KDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL7476482 | 0.78 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRMGAM | |
| SCHEMBL3650453 | 0.78 | HCAR2 (0.48) | HCAR2POLBNAPRTTTRTSHR | |
| SCHEMBL199221 | 0.78 | TTR (0.54) | HCAR2POLBNAPRTTTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074611-A1 | PRMT5 INHIBITORS | Ryvu Therapeutics S.A. (PL) | 2024-04-11 | — | — | WO | disclosed |