Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385410 | 1.00 | NOS3 (0.41) | NOS3NOS1HTR1DHTR1BMAPT | |
| Hydrochloric Acid SCHEMBL8386555 | 0.88 | NOS3 (0.41) | NOS3NOS1HTR1DHTR1BMAPT | |
| Hydrochloric Acid SCHEMBL30909117 | 0.88 | NOS3 (0.41) | NOS3NOS1HTR1DHTR1BMAPT | |
| SCHEMBL8381682 | 0.86 | NOS3 (0.44) | NOS3NOS1HTR1DHTR1BMAPT | |
| SCHEMBL8708059 | 0.84 | NOS1 (0.38) | NOS3NOS1HTR1DHTR1BMAPT | |
| SCHEMBL8385406 | 0.81 | NOS3 (0.42) | NOS3NOS1HTR1DHTR1BMAPT | |
| SCHEMBL8708647 | 0.81 | NOS3 (0.51) | NOS3NOS1HTR1DHTR1BMAPT | |
| Hydrochloric Acid SCHEMBL8709283 | 0.80 | NOS3 (0.52) | NOS3NOS1HTR1DHTR1BMAPT | |
| SCHEMBL30908958 | 0.80 | HTR6 (0.34) | NOS3NOS1MAPTLMNA | |
| SCHEMBL8385366 | 0.80 | NOS3 (0.41) | NOS3NOS1HTR1DHTR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |