Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VPS4B | O75351 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.36 |
| ▸ | DRD2 | P14416 | 9/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101509 | 1.00 | VPS4B (0.42) | VPS4BVCPHTR1FSLC6A4DRD2 | |
| SCHEMBL30909244 | 0.90 | HTR1F (0.39) | HTR1FHTR1AMAPTALDH1A1KMT2A | |
| SCHEMBL8100845 | 0.90 | HTR1F (0.39) | HTR1FHTR1AMAPTALDH1A1KMT2A | |
| SCHEMBL8109141 | 0.86 | KMT2A (0.38) | VPS4BVCPHTR1FSLC6A4DRD2 | |
| Glycolic Acid SCHEMBL30908912 | 0.83 | VPS4B (0.37) | VPS4BVCPHTR1FSLC6A4DRD2 | |
| SCHEMBL8101211 | 0.80 | VPS4B (0.37) | VPS4BVCPHTR1FSLC6A4HTR1A | |
| SCHEMBL8109143 | 0.77 | VPS4B (0.36) | VPS4BVCPHTR1FSLC6A4DRD2 | |
| SCHEMBL8109130 | 0.76 | KMT2A (0.39) | HTR1FHTR1AMAPTKMT2ARORC | |
| Hydrochloric Acid SCHEMBL7657938 | 0.75 | HTR1F (0.55) | HTR1FDRD2HTR1AALDH1A1 | |
| Glycolic Acid SCHEMBL30908766 | 0.74 | KMT2A (0.37) | HTR1FDRD2HTR1AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |