Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL30908766 | 0.97 | KMT2A (0.37) | KMT2AABL1ALPLALPIALPG | |
| SCHEMBL8109141 | 0.90 | KMT2A (0.38) | KMT2AABL1ALPLALPIALPG | |
| Glycolic Acid SCHEMBL30908912 | 0.87 | VPS4B (0.37) | KMT2AABL1ALPLALPIALPG | |
| SCHEMBL8100845 | 0.86 | HTR1F (0.39) | KMT2AABL1ALPLALPIALPG | |
| SCHEMBL30909244 | 0.86 | HTR1F (0.39) | KMT2AABL1ALPLALPIALPG | |
| Hydrochloric Acid SCHEMBL7657938 | 0.83 | HTR1F (0.55) | HTR1FHTR1AHTR1DHTR1B | |
| SCHEMBL8116970 | 0.80 | HTR1D (0.39) | HTR1FHTR1AHTR1DHTR1BSIGMAR1 | |
| SCHEMBL7661452 | 0.79 | EGFR (0.41) | HTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7657139 | 0.79 | EGFR (0.42) | HTR1AHTR1DHTR1B | |
| Hexanoate SCHEMBL8110191 | 0.77 | HTR1A (0.39) | HTR1FHTR1AHTR1DHTR1BROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749962-B1 | 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta(7,6-B)indoles | LILLY CO ELI (US) | 2000-11-02 | — | — | EP | disclosed |
| US-5814653-A | SUMATRIPTAN FOR RELIEF OF MIGRAINE PAIN AND OTHER DISORDERS ASSOCIATED WITH PEPTIDE EXTRAVASATION DIE TO STUMULATION OF THE TRIGEMINAL GANGLIA; 5-HT 1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |
| US-5708187-A | MIGRANE HEADACHES | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0749962-A1 | 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta(7,6-B)indoles | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |