Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | CCR2 | P41597 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9031666 | 0.89 | OPRM1 (0.57) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| SCHEMBL9030215 | 0.83 | ADRA1D (0.63) | OPRM1OPRK1OPRL1ADRA1D | |
| Hydrochloric Acid SCHEMBL9031606 | 0.80 | OPRM1 (0.79) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9048518 | 0.78 | OPRM1 (0.58) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9049148 | 0.78 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| SCHEMBL5385661 | 0.78 | OPRM1 (0.64) | OPRM1OPRK1OPRL1CCR2ADRA1D | |
| SCHEMBL31143224 | 0.77 | ADRA1D (0.57) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| Oxalic Acid SCHEMBL9048237 | 0.76 | OPRM1 (0.55) | OPRM1OPRK1OPRL1HTR6KCNH2 | |
| SCHEMBL14280723 | 0.76 | OPRM1 (1.00) | OPRM1OPRK1OPRL1ADRA1D | |
| Oxalic Acid SCHEMBL9049191 | 0.76 | OPRM1 (0.56) | OPRM1OPRK1OPRL1HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |