Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489098 | 1.00 | HTR1A (0.48) | HTR1ADRD2NOS3NOS1MAPT | |
| SCHEMBL7483212 | 0.86 | NOS3 (0.62) | HTR1ADRD2NOS3NOS1MAPT | |
| SCHEMBL7488364 | 0.83 | HTR1F (0.58) | HTR1ADRD2NOS3NOS1 | |
| SCHEMBL7484391 | 0.81 | NOS3 (0.49) | HTR1ADRD2NOS3NOS1 | |
| SCHEMBL30908871 | 0.81 | KDM4E (0.52) | HTR1ADRD2 | |
| SCHEMBL7489869 | 0.81 | KDM4E (0.52) | HTR1ADRD2 | |
| SCHEMBL7480204 | 0.81 | HTR1A (0.49) | HTR1ADRD2NOS3NOS1MAPT | |
| SCHEMBL7479518 | 0.80 | NOS3 (0.49) | HTR1ADRD2NOS3NOS1 | |
| SCHEMBL7490018 | 0.80 | NOS3 (0.49) | HTR1ADRD2NOS3NOS1 | |
| SCHEMBL7482253 | 0.80 | NOS3 (0.47) | HTR1ADRD2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |