Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 20/20 | 0.75 |
| ▸ | HTR1A | P08908 | 16/20 | 0.75 |
| ▸ | HTR1D | P28221 | 14/20 | 0.75 |
| ▸ | HTR1B | P28222 | 14/20 | 0.75 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383872 | 0.93 | HTR1F (0.72) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8387305 | 0.90 | HTR1F (0.73) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7012312 | 0.86 | HTR1F (1.00) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7011819 | 0.83 | HTR1F (0.81) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7009843 | 0.82 | HTR1F (0.77) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7009243 | 0.80 | HTR1F (0.79) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL7013892 | 0.79 | HTR1F (0.77) | HTR1FHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL8723729 | 0.77 | HTR1A (0.42) | HTR1FHTR1AHTR1DHTR1B | |
| SCHEMBL8386474 | 0.75 | HTR1D (0.51) | HTR1FHTR1AHTR1DHTR1B | |
| SCHEMBL8387337 | 0.72 | HTR1F (0.56) | HTR1FHTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |