Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557055 | 0.97 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL10937862 | 0.81 | RIPK1 (0.64) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL2746269 | 0.80 | RIPK1 (0.67) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL1709321 | 0.78 | RIPK1 (1.00) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL1709337 | 0.78 | RIPK1 (0.75) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL27776096 | 0.77 | RIPK1 (0.59) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL27776098 | 0.77 | RIPK1 (0.59) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL25464672 | 0.77 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL10990271 | 0.77 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTOPRK1 | |
| SCHEMBL7438658 | 0.77 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117860606-A | Anti-aging cosmetic composition and application thereof | 杭州毛戈平科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117860606-A | Anti-aging cosmetic composition and application thereof | 杭州毛戈平科技有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-117860606-A | Anti-aging cosmetic composition and application thereof | 杭州毛戈平科技有限公司 | 2024-04-12 | — | — | CN | disclosed |