Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.49 |
| ▸ | CTSD | P07339 | 3/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21724279 | 0.88 | BACE1 (0.52) | BACE1CTSSCTSKREN | |
| SCHEMBL21724277 | 0.88 | BACE1 (0.52) | BACE1CTSSCTSKREN | |
| SCHEMBL21737915 | 0.88 | BACE1 (0.48) | BACE1PSENENCTSSCTSKREN | |
| SCHEMBL30511412 | 0.88 | BACE1 (0.48) | BACE1PSENENCTSSCTSKREN | |
| SCHEMBL30910800 | 0.88 | BACE1 (0.48) | BACE1PSENENCTSSCTSKREN | |
| SCHEMBL22989798 | 0.87 | CTSD (0.44) | BACE1CTSDPSENENKLK5CTSS | |
| SCHEMBL29484068 | 0.86 | PSENEN (0.47) | CTSDPSENENKLK5CTSSCTSK | |
| Hydrochloric Acid SCHEMBL30511421 | 0.86 | BACE1 (0.48) | BACE1PSENENCTSSCTSKREN | |
| SCHEMBL23080079 | 0.85 | PSENEN (0.48) | CTSDPSENENKLK5CTSSCTSK | |
| SCHEMBL30910744 | 0.83 | CTSL (0.51) | BACE1CTSSCTSKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | FLAGSHIP PIONEERING INNOVATIONS V INC (US) | 2024-12-05 | — | — | US | disclosed |
| US-11998610-B2 | Conjugates and methods of using the same | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2024-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11998610-B2 | Conjugates and methods of using the same | CD47, CD44, CD74 | BACE1 4427/4885CTSD 1346/4885PSENEN 4454/4885 |
| US-20240398966-A1 | CONJUGATES AND METHODS OF USING THE SAME | CD47, CD44, CD74 | BACE1 4427/4885CTSD 1346/4885PSENEN 4454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.