Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21910195 | 1.00 | FFAR2 (0.45) | FFAR2APLNRS1PR3S1PR1BRD4 | |
| SCHEMBL21831494 | 0.90 | LMNA (0.44) | S1PR3S1PR1BRD4S1PR4S1PR2 | |
| SCHEMBL21831287 | 0.89 | APLNR (0.46) | FFAR2APLNRDRD2KMT2A | |
| SCHEMBL30910915 | 0.89 | APLNR (0.46) | FFAR2APLNRDRD2KMT2A | |
| SCHEMBL21831379 | 0.85 | BRD4 (0.46) | S1PR3S1PR1BRD4S1PR4S1PR2 | |
| SCHEMBL30910928 | 0.85 | BRD4 (0.46) | S1PR3S1PR1BRD4S1PR4S1PR2 | |
| SCHEMBL133374 | 0.82 | CYP11B1 (0.44) | APLNRHPGDLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14033601 | 0.79 | S1PR3 (0.45) | S1PR3S1PR1S1PR4S1PR2RAB9A | |
| SCHEMBL21831035 | 0.79 | S1PR3 (0.44) | S1PR3S1PR1BRD4S1PR4S1PR2 | |
| SCHEMBL21911304 | 0.79 | FFAR2 (0.48) | FFAR2APLNRS1PR3S1PR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654621-B | Substituted naphthyridinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-05-14 | — | — | CN | disclosed |