Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677041 | 0.80 | MEN1 (0.35) | FAAHELANECTSG | |
| SCHEMBL21359938 | 0.76 | ELANE (0.33) | FAAHELANECTSG | |
| SCHEMBL26097506 | 0.76 | ELANE (0.33) | FAAHELANECTSG | |
| SCHEMBL26099596 | 0.76 | ELANE (0.33) | FAAHELANECTSG | |
| SCHEMBL30911168 | 0.76 | MEN1 (0.39) | ELANECTSG | |
| SCHEMBL18787939 | 0.73 | ELANE (0.34) | FAAHELANECTSG | |
| SCHEMBL21358570 | 0.71 | ELANE (0.35) | ELANECTSG | |
| SCHEMBL17491758 | 0.68 | FAAH (0.44) | FAAH | |
| SCHEMBL22127554 | 0.66 | ALDH1A1 (0.45) | GAA | |
| SCHEMBL5992716 | 0.65 | ELANE (0.35) | FAAHELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598915-A2 | TETHERED HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | Amgen Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076670-A2 | TETHERED HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |