Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 9/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30912557 | 0.88 | DHODH (0.40) | DHODHTYK2 | |
| SCHEMBL19531954 | 0.84 | IL4I1 (0.39) | HCAR1DHODH | |
| SCHEMBL28462395 | 0.83 | TYK2 (0.33) | CYP2A13DHODHTYK2 | |
| SCHEMBL22051977 | 0.81 | TYK2 (0.38) | TYK2 | |
| SCHEMBL20688017 | 0.80 | HCAR1 (0.38) | HCAR1CHRM2CHRM4CHRM1DHODH | |
| SCHEMBL21659036 | 0.78 | HCAR1 (0.40) | HCAR1CHRM2CHRM4CHRM1DHODH | |
| SCHEMBL21659038 | 0.76 | TYK2 (0.36) | HCAR1CHRM2CHRM4CHRM1DHODH | |
| SCHEMBL20687697 | 0.76 | TYK2 (0.46) | TYK2 | |
| SCHEMBL21246029 | 0.76 | CNR2 (0.39) | TYK2 | |
| SCHEMBL17682621 | 0.74 | P2RX7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619406-A1 | TRICYCLIC COMPOUNDS | Schrödinger, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-118843626-A | Heterocyclic compounds as DYRK1A inhibitors | 普罗塞纳生物科学有限公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2024107393-A1 | TRICYCLIC COMPOUNDS | SCHRÖDINGER, INC. (US) | 2024-05-23 | — | — | WO | disclosed |