Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23088757 | 0.81 | MAOB (0.42) | ALDH1A1KMT2ATNKS2 | |
| SCHEMBL30913033 | 0.81 | MAOB (0.42) | ALDH1A1KMT2ATNKS2 | |
| SCHEMBL23088753 | 0.80 | KMT2A (0.40) | ALDH1A1HTR2CKMT2AHTR2AHTR2B | |
| SCHEMBL23088767 | 0.79 | KMT2A (0.47) | ALDH1A1KMT2A | |
| SCHEMBL29740756 | 0.79 | KMT2A (0.47) | ALDH1A1KMT2A | |
| SCHEMBL23088782 | 0.77 | CYP19A1 (0.43) | ALDH1A1HTR2CKMT2A | |
| SCHEMBL30913024 | 0.77 | CYP19A1 (0.43) | ALDH1A1HTR2CKMT2A | |
| SCHEMBL30913032 | 0.75 | KMT2A (0.37) | ALDH1A1KMT2A | |
| SCHEMBL23088790 | 0.74 | POLB (0.42) | HTR2CKMT2AHTR2AHTR2B | |
| SCHEMBL23088758 | 0.74 | KMT2A (0.40) | ALDH1A1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084822-A | Preparation method for synthesizing chiral sulfonamide through nickel catalytic asymmetric reduction and chiral sulfonamide compound | 中国科学院大连化学物理研究所 | 2024-05-28 | — | — | CN | disclosed |