Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23088782 | 1.00 | CYP19A1 (0.43) | CYP19A1HTR2CALDH1A1ALDH2MEN1 | |
| SCHEMBL30913033 | 0.84 | MAOB (0.42) | CYP19A1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL23088757 | 0.84 | MAOB (0.42) | CYP19A1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29740756 | 0.83 | KMT2A (0.47) | CYP19A1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL23088767 | 0.83 | KMT2A (0.47) | CYP19A1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL23088770 | 0.83 | SLC6A3 (0.41) | HTR2CGAAMAPT | |
| SCHEMBL23088772 | 0.81 | GAA (0.48) | CYP19A1ALDH1A1ALDH2MEN1KMT2A | |
| SCHEMBL23088750 | 0.78 | SLC6A2 (0.39) | HTR2CMEN1KMT2A | |
| SCHEMBL30913023 | 0.77 | ALDH1A1 (0.49) | HTR2CALDH1A1KMT2A | |
| SCHEMBL7640761 | 0.77 | PTGDR2 (0.50) | HTR2CALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084822-A | Preparation method for synthesizing chiral sulfonamide through nickel catalytic asymmetric reduction and chiral sulfonamide compound | 中国科学院大连化学物理研究所 | 2024-05-28 | — | — | CN | disclosed |