Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30913026 | 0.77 | KMT2A (0.36) | KMT2AMEN1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30913023 | 0.75 | ALDH1A1 (0.49) | KMT2AALDH1A1 | |
| SCHEMBL24074876 | 0.75 | CA2 (0.39) | AR | |
| SCHEMBL24074874 | 0.75 | CA2 (0.42) | ALDH1A1TSHRARLMNA | |
| SCHEMBL24075509 | 0.75 | MAPT (0.39) | MAOAMAOBAKR1C3 | |
| SCHEMBL23088767 | 0.74 | KMT2A (0.47) | KMT2AMEN1ALDH1A1TSHRMAOB | |
| SCHEMBL29740756 | 0.74 | KMT2A (0.47) | KMT2AMEN1ALDH1A1TSHRMAOB | |
| SCHEMBL30913033 | 0.73 | MAOB (0.42) | KMT2AMEN1ALDH1A1MAOBLMNA | |
| SCHEMBL23088757 | 0.73 | MAOB (0.42) | KMT2AMEN1ALDH1A1MAOBLMNA | |
| SCHEMBL24075587 | 0.72 | GSTP1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084822-A | Preparation method for synthesizing chiral sulfonamide through nickel catalytic asymmetric reduction and chiral sulfonamide compound | 中国科学院大连化学物理研究所 | 2024-05-28 | — | — | CN | disclosed |