SCHEMBL30913604

SCHEMBL30913604

c1ccc2c(C(c3ccncc3)c3c[nH]c4ccccc34)c[nH]c2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NR3C1 P04150 1/20 0.54
PGR P06401 1/20 0.54
NR3C2 P08235 1/20 0.54
AR P10275 1/20 0.54
MGAM O43451 3/20 0.53
GAA P10253 3/20 0.53
SI P14410 3/20 0.53
MGAM2 Q2M2H8 3/20 0.53
IMPDH2 P12268 1/20 0.53
MAPK1 P28482 1/20 0.53
HSD17B10 Q99714 1/20 0.53
AHR P35869 2/20 0.52
GPR84 Q9NQS5 3/20 0.50
FFAR1 O14842 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7290548 1.00 MAPT (0.59) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL3343111 0.85 MAPT (0.69) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL30040360 0.85 MAPT (0.69) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL1992184 0.83 MAPT (0.61) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL7296123 0.82 MAPT (0.55) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL29871649 0.82 MAPT (0.55) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL10717194 0.82 NR3C1 (0.73) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL29885627 0.81 MAPT (0.65) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL8592636 0.81 MAPT (0.65) MAPTMEN1KMT2ANR3C1PGR
SCHEMBL26873731 0.80 MAPT (0.48) MAPTMEN1KMT2ANR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024102444-A1 INSECTICIDAL COMPOUNDS PLUTON BIOSCIENCES, INC. (US) 2024-05-16 WO disclosed