SCHEMBL309141

SCHEMBL309141

CCCC(O)(CCC)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
CYP2C19 P33261 1/20 0.37
FDPS P14324 10/20 0.36
GGPS1 O95749 6/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12297009 0.88 FDPS (0.39) ALDH1A1CYP2C19FDPSGGPS1
SCHEMBL16074669 0.86 FDPS (0.32) ALDH1A1CYP2C19FDPSTSHR
SCHEMBL14561037 0.85 FDPS (0.36) ALDH1A1CYP2C19FDPSGGPS1TSHR
SCHEMBL27867932 0.82 FDPS (0.34) ALDH1A1CYP2C19FDPSGGPS1TSHR
SCHEMBL3686300 0.79 TSHR (0.35) FDPSTSHR
SCHEMBL12224081 0.78 FDPS (0.37) FDPSGGPS1
SCHEMBL27916083 0.78 FDPS (0.45) FDPSGGPS1TSHR
SCHEMBL27934711 0.78 FDPS (0.45) FDPSGGPS1TSHR
SCHEMBL3681752 0.78 TSHR (0.32) TSHR
SCHEMBL1153681 0.77 FDPS (0.33) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119002096-A Method for manufacturing contact lens 望隼科技股份有限公司 2024-11-22 CN claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
EP-3976362-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2022-04-06 EP claimed
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 US claimed
WO-2020240440-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2020-12-03 WO claimed
US-8506856-B2 Method for making silicone hydrogel contact lenses NOVARTIS AG (CH) 2013-08-13 US claimed
EP-2232304-A2 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Novartis AG (CH) 2010-09-29 EP claimed
WO-2009076143-A2 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2009-06-18 WO claimed
US-20090146330-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2009-06-11 US claimed
EP-0908744-B1 Silicone hydrogel polymers JOHNSON & JOHNSON VISION PROD (US) 2002-12-18 EP claimed
EP-0902794-B1 CATALYST SASOL TECH PTY LTD (ZA) 2000-08-23 EP claimed
US-6020445-A Silicone hydrogel polymers JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 2000-02-01 US claimed
EP-0908744-A1 Silicone hydrogel polymers JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1999-04-14 EP claimed
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 WO disclosed
WO-2026099827-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC. (CH) 2026-05-15 WO disclosed
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC (CH) 2026-05-14 US disclosed
US-4297240-A AND A POLYMERIZATION CATALYST MADE FROM ALKALINE METAL ALCOHOLATES AND ALKYL OR CYCLOALKYL ALUMINUM AND MAGNESIUM COMPOUNDS THE GENERAL TIRE & RUBBER COMPANY (US) 1981-10-27 US disclosed
US-4260519-A POLYMERIZATION CATALYSTS THE GENERAL TIRE & RUBBER COMPANY (US) 1981-04-07 US disclosed
US-4260712-A USED IN COMPLEXES WITH A HYDROCARBYL LITHIUM COMPOUND AS A POLYMERIZATION CATALYST THE GENERAL TIRE & RUBBER COMPANY (US) 1981-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES RAD51, ERCC1, LANCL2 ALDH1A1 1638/4885CYP2C19 2235/4885FDPS 4557/4885
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA ALDH1A1 3383/4885CYP2C19 1581/4885FDPS 3030/4885
US-20200376787-A1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES COIL, CRYAB, CRYAA ALDH1A1 3383/4885CYP2C19 1581/4885FDPS 3030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.