Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAMP3 | O60896 | 15/20 | 0.50 |
| ▸ | CALCR | P30988 | 15/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914561 | 0.92 | MAPK8 (0.51) | RAMP3CALCRMAPK8MAPK9MAPK10 | |
| SCHEMBL30262325 | 0.89 | RAMP3 (0.51) | RAMP3CALCRKEAP1 | |
| SCHEMBL31489174 | 0.88 | NMUR2 (0.46) | RAMP3CALCR | |
| SCHEMBL31575689 | 0.87 | RAMP3 (0.49) | RAMP3CALCRKEAP1EP300HIF1A | |
| SCHEMBL30974226 | 0.86 | RAMP3 (0.50) | RAMP3CALCRMAPK8MAPK9MAPK10 | |
| SCHEMBL29496452 | 0.85 | PLK1 (0.44) | RAMP3CALCR | |
| SCHEMBL30099507 | 0.85 | RAMP3 (0.57) | RAMP3CALCRMAPK8MAPK9MAPK10 | |
| SCHEMBL29776766 | 0.85 | MAPK8 (0.58) | RAMP3CALCRMAPK8MAPK9MAPK10 | |
| SCHEMBL29679604 | 0.85 | RAMP3 (0.57) | RAMP3CALCR | |
| SCHEMBL29823805 | 0.84 | RAMP3 (0.39) | RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156973-A1 | OSTEOTROPIC COMPOSITIONS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2024-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156973-A1 | OSTEOTROPIC COMPOSITIONS AND USES THEREOF | SOST, BMP2, BMP6 | RAMP3 1626/4885CALCR 15/4885MAPK8 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.