SCHEMBL30914580

SCHEMBL30914580

O=C(O)c1cccc([Se]c2c[nH]c3ccccc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
MAP2K4 P45985 1/20 0.47
MAPKAPK3 Q16644 1/20 0.47
MAPK6 Q16659 1/20 0.47
GPR84 Q9NQS5 3/20 0.43
CTNNB1 P35222 1/20 0.43
WNT3A P56704 1/20 0.43
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214081 0.88 ALDH1A1 (0.48) MAPK1GPR84CTNNB1WNT3ANPC1
SCHEMBL28827211 0.80 ATM (0.45) GPR84ALDH1A1MEN1KMT2AMAPT
SCHEMBL28907736 0.73 ATM (0.52) MAPK1GPR84ALDH1A1MEN1KMT2A
SCHEMBL22634965 0.72 GPR84 (0.65) MAPK1MAP2K4MAPKAPK3MAPK6GPR84
SCHEMBL5424839 0.69 PTPN1 (0.61) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL5429419 0.69 PTPN1 (0.61) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL16720250 0.69 MAPK1 (0.46) MAPK1MAP2K4MAPKAPK3MAPK6GPR84
SCHEMBL6816146 0.69 HDAC3 (0.50) MAPK1MAP2K4MAPKAPK3MAPK6GPR84
SCHEMBL9353651 0.68 CA12 (0.56) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL5688081 0.66 CA12 (0.54) ALDH1A1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063434-A 3- (Indole-3-seleno) benzamide compound and synthetic method and application thereof 浙江工业大学 2024-05-24 CN disclosed