Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15402211 | 0.98 | FFAR4 (0.48) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL16023959 | 0.94 | LMNA (0.52) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL17676330 | 0.92 | CA2 (0.46) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL14899675 | 0.91 | TSHR (0.48) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL22602510 | 0.89 | LMNA (0.52) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL8895596 | 0.89 | ALDH1A1 (0.41) | LMNACES2CES1TSHRTDP1 | |
| SCHEMBL6677823 | 0.86 | CA2 (0.48) | FFAR4FFAR1LMNATSHRTDP1 | |
| SCHEMBL7152069 | 0.86 | CA2 (0.53) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL9700954 | 0.86 | CA2 (0.53) | FFAR4FFAR1LMNACES2CES1 | |
| SCHEMBL15545284 | 0.85 | LMNA (0.52) | FFAR4FFAR1LMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102730-A1 | LIPIDS AND NANOPARTICLE COMPOSITIONS FOR DELIVERING POLYNUCLEOTIDES | ORNA THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | WO | disclosed |