Arginine

Arginine

SCHEMBL309164

N=C(N)NCCC[C@H](N)C(=O)[O-].N=C(N)NCCC[C@H](N)C(=O)[O-].[Zn+2]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACES1PR1S1PR4S1PR5

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 2/20 0.39
▸ OTC P00480 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ DDAH1 O94760 1/20 0.36
▸ NPY4R P50391 7/20 0.36
▸ NPY1R P25929 5/20 0.36
▸ NPY2R P49146 4/20 0.36
▸ NPY5R Q15761 4/20 0.36
▸ GNAI3 P08754 1/20 0.34
▸ GNAO1 P09471 1/20 0.34
▸ GNAI1 P63096 1/20 0.34
▸ NOS1 P29475 3/20 0.33
▸ NOS3 P29474 2/20 0.33
▸ NOS2 P35228 2/20 0.33
▸ RRM1 P23921 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL21081868 0.98 DPP7 (0.38) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL4273378 0.98 DPP7 (0.40) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL7713117 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL21808680 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL16194704 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL3749742 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL1766115 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL6711066 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL7154973 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2
Arginine SCHEMBL9238731 0.96 DPP7 (0.39) DPP7OTCALOX15MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521322-B2 Foaming oral care compositions THE PROCTER & GAMBLE COMPANY (US) 2026-01-13 — — US claimed
EP-3400260-B2 SCAVENGER COMPOSITIONS FOR SULFUR SPECIES INNOPHOS INC (US) 2025-03-19 — — EP claimed
CN-119632148-A Powder-free granular composite premixed feed and preparation method thereof 丰县新中牧饲料有限公司 2025-03-18 — — CN claimed
CN-118496683-A Scavenger composition for sulfur species 伊诺弗斯公司 2024-08-16 — — CN claimed
US-20240197578-A1 Foaming Oral Care Compositions PROCTER & GAMBLE (US) 2024-06-20 — — US claimed
CN-118160928-A Composition for promoting water supplementing and preparation method and application thereof 南京盛德创赢生物科技有限公司 2024-06-11 — — CN claimed
EP-3359138-B1 DIETARY SUPPLEMENTATION TO ACHIEVE OXY-REDOX HOMEOSTASIS AND EPIGENETIC STABILITY PARTHENOGEN SAGL (CH) 2024-04-24 — — EP claimed
US-11944694-B2 Foaming oral care compositions THE PROCTER & GAMBLE COMPANY (US) 2024-04-02 — — US claimed
CN-112655846-B Organic trace element composite package for shrimps and crabs as well as preparation method and application thereof 长沙兴嘉生物工程股份有限公司 2023-10-31 — — CN claimed
WO-2023007088-A1 FOOD SUPPLEMENT FOR COMBATING FEMALE AND MALE INFERTILITY NURIBIOL (FR) 2023-02-02 — — WO claimed
US-20040105894-A1 Trace Metals synergized copper nucleotides and copper glycosides for anti-aging and antiviral compositions GUPTA SHYAM K (US) 2004-06-03 — — US claimed
US-20030211172-A1 Composition and method for substantially reducing the deleterious effects of alcohol on the body JONES JEREMY PARK (US) 2003-11-13 — — US claimed
US-6447809-B1 MIXTURES OF MICROCRYSTALLINE HYDROXYAPATITE, CHOLECALCIFEROL AND IPRIFLAVONE ADMINISTERED AS OSTEOBLASTS STIMULANTS FOR PREVENTION OF OSTEOPOROSIS METAGENICS, INC. 2002-09-10 — — US claimed
US-20020001632-A1 Method and composition for the treatment of benign prostate hypertrophy (BPH) and prevention of prostate cancer REVEL CHASE (PA) 2002-01-03 — — US claimed
US-20020001633-A1 Method and composition for the treatment of benign prostate hypertrophy (BPH) and prevention of prostate cancer REVEL CHASE (US) 2002-01-03 — — US claimed
EP-0672500-B1 Polymeric mask for sandblasting and method for its use AICELLO CHEMICAL CO (JP) 2001-12-19 — — EP claimed
EP-0672500-A2 Polymeric mask for sandblasting and method for its use AICELLO CHEMICAL CO. LTD. (JP) 1995-09-20 — — EP claimed
US-5234698-A Increases amount of prostatic antibacterial factor FAHIM MOSTAFA S (US) 1993-08-10 — — US claimed
US-5071658-A Increase antibacterial factor and inhibits growth; antiandrogen agent FAHIM MOSTAFA S (US) 1991-12-10 — — US claimed
US-4946688-A ANTIGROWTH AGENTS FAHIM MOSTAFA S (US) 1990-08-07 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197578-A1 Foaming Oral Care Compositions FOS, STOM, UGCG DPP7 4174/4885OTC 245/4885ALOX15 1569/4885
US-11944694-B2 Foaming oral care compositions FOS, STOM, UGCG DPP7 4174/4885OTC 245/4885ALOX15 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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