Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149657 | 1.00 | MAPT (0.42) | MAPTMEN1KMT2AAPPALDH1A1 | |
| SCHEMBL13149758 | 0.89 | ACHE (0.54) | MAPTMEN1KMT2AAPPALDH1A1 | |
| SCHEMBL791664 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2AAPPALDH1A1 | |
| SCHEMBL28553350 | 0.86 | APP (0.40) | APPCYP3A4TSHR | |
| SCHEMBL1986810 | 0.86 | APP (0.40) | APPCYP3A4TSHR | |
| SCHEMBL25837 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL7893866 | 0.80 | — | — | |
| SCHEMBL2703573 | 0.78 | KIF11 (0.37) | APPKIF11 | |
| SCHEMBL9296155 | 0.77 | KIF11 (0.45) | MAPTMEN1KMT2AAPPALDH1A1 | |
| SCHEMBL7806577 | 0.76 | TSHR (0.53) | MAPTMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | PAH, TSNAX, ZFX | MAPT 1452/4885MEN1 286/4885KMT2A 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.