Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200527 | 0.89 | KIF11 (0.54) | KIF11ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL1140694 | 0.80 | KIF11 (0.46) | KIF11ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL9295526 | 0.78 | ALDH1A1 (0.56) | KIF11ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL8952160 | 0.78 | ESR1 (0.52) | KIF11APPALDH1A1KDM4EMAPT | |
| SCHEMBL17789212 | 0.78 | ACHE (0.56) | KIF11ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL13149657 | 0.77 | MAPT (0.42) | KIF11APPALDH1A1TDP1KDM4E | |
| SCHEMBL3091933 | 0.77 | MAPT (0.42) | KIF11APPALDH1A1TDP1KDM4E | |
| SCHEMBL25837 | 0.75 | — | — | |
| SCHEMBL9296088 | 0.74 | PTPN1 (0.44) | KIF11APPALDH1A1TDP1KDM4E | |
| SCHEMBL22694326 | 0.74 | ALDH1A1 (0.50) | KIF11APPALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344982-A | Adhesives, composites, films, matrices; solvent resistance, modulus, high glass transition temperature | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1994-09-06 | — | — | US | disclosed |