SCHEMBL30919475

SCHEMBL30919475

CC(=O)N(Cc1ccc(C)cc1C)NC(=O)c1cc(C)nnc1Oc1cccc(C2CC2)c1F

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
CCR2 P41597 1/20 0.30
NOTUM Q6P988 1/20 0.30
SYK P43405 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31718970 0.94 MEN1 (0.30) MEN1LMNAKMT2A
SCHEMBL31719026 0.94 MEN1 (0.30) MEN1LMNAKMT2A
SCHEMBL30919503 0.92 SYK (0.31) SYK
SCHEMBL30919485 0.91 KDM4C (0.32) NOTUMKDM4C
SCHEMBL30919504 0.88 HTT (0.31) MEN1LMNAKMT2ADRD2DRD4
SCHEMBL30919502 0.88 MEN1 (0.32) MEN1LMNAKMT2ADRD2DRD4
SCHEMBL31719009 0.88 CCR2 (0.33) MEN1LMNAKMT2ACCR2RAF1
SCHEMBL30919498 0.86 MEN1 (0.30) MEN1LMNAKMT2A
SCHEMBL30919482 0.80 SCN9A (0.37) LMNA
SCHEMBL31495982 0.80 TAS1R3 (0.35) MEN1LMNAKMT2ASYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143336-A1 HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT 日本曹達株式会社 2024-07-04 WO disclosed