SCHEMBL3092001

SCHEMBL3092001

CC(C)C(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.57
ALDH1A1 P00352 4/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
NPSR1 Q6W5P4 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
CYP2D6 P10635 1/20 0.52
CYP3A4 P08684 3/20 0.50
KMT2A Q03164 1/20 0.48
HDAC1 Q13547 4/20 0.47
HDAC3 O15379 3/20 0.47
HDAC4 P56524 3/20 0.47
HDAC7 Q8WUI4 3/20 0.47
HDAC2 Q92769 3/20 0.47
HDAC10 Q969S8 3/20 0.47
HDAC11 Q96DB2 3/20 0.47
HDAC8 Q9BY41 3/20 0.47
HDAC6 Q9UBN7 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19984712 0.86 LMNA (0.59) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL29110135 0.86 LMNA (0.70) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL19660031 0.84 HDAC1 (0.45) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL27484428 0.84 LMNA (0.58) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL28830240 0.83 LMNA (0.65) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL17583583 0.82 UGT2B7 (0.53) ALDH1A1TDP1L3MBTL1CES2CES1
SCHEMBL7827857 0.81 CYP2D6 (0.74) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL29719387 0.81 TDP1 (0.59) LMNAALDH1A1SMN1; SMN2NPSR1TDP1
SCHEMBL10963416 0.81 KMT2A (0.48) LMNAALDH1A1SMN1; SMN2NPSR1L3MBTL1
SCHEMBL66944 0.80 CYP2D6 (0.73) LMNACYP2D6KMT2AHDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7008975-B2 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-03-07 US claimed
US-20050043427-A1 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-02-24 US claimed
US-6815034-B2 FOR USE AS LENSES FOR CLOCKS, TELEVISION TUBES/MONITORS, LIQUID CRYSTAL DISPLAYS, SAFETY GLASSES AND PROTECTIVE HELMETS; HIGH HARDNESS, LOW SHRINKAGE RATE SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-11-09 US claimed
US-20030199601-A1 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-10-23 US claimed
US-20170369462-A1 Modulation of Bacterial Quorum Sensing with Synthetic Ligands NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-12-28 US disclosed
US-9796694-B2 Modulation of bacterial quorum sensing with synthetic ligands WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-10-24 US disclosed
US-9796694-B2 Modulation of bacterial quorum sensing with synthetic ligands WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-10-24 US disclosed
US-20150080349-A1 MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2015-03-19 US disclosed
US-8815943-B2 Modulation of bacterial quorum sensing with synthetic ligands WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2014-08-26 US disclosed
US-8236906-B2 Polyamide-imide resin, process for production of polyamide resin, and curable resin composition HITACHI CHEMICAL COMPANY, LTD. (JP) 2012-08-07 US disclosed
US-20110212860-A1 Modulation of Bacterial Quorum Sensing With Synthetic Ligands WISCONSIN ALUMNI RESEARCH FOUNDATION 2011-09-01 US disclosed
US-7910622-B2 Modulation of bacterial quorum sensing with synthetic ligands WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-03-22 US disclosed
US-20100234554-A1 Polyamide-Imide Resin, Process for Production of Polyamide Resin, and Curable Resin Composition HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-09-16 US disclosed
US-20080312319-A1 Modulation of Bacterial Quorum Sensing with Synthetic Ligands NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-12-18 US disclosed
US-7304168-B2 Photo-caged fluorescent molecules BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 2007-12-04 US disclosed
US-7008975-B2 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-03-07 US disclosed
US-20050043427-A1 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-02-24 US disclosed
US-6815034-B2 FOR USE AS LENSES FOR CLOCKS, TELEVISION TUBES/MONITORS, LIQUID CRYSTAL DISPLAYS, SAFETY GLASSES AND PROTECTIVE HELMETS; HIGH HARDNESS, LOW SHRINKAGE RATE SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-11-09 US disclosed
US-20030199601-A1 Light-curable resin composition having antistatic property SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170369462-A1 Modulation of Bacterial Quorum Sensing with Synthetic Ligands AHCYL1, EBPL, AIP LMNA 3895/4885ALDH1A1 2885/4885SMN1; SMN2 4883/4885
US-20110212860-A1 Modulation of Bacterial Quorum Sensing With Synthetic Ligands AHCYL1, EBPL, AIP LMNA 3895/4885ALDH1A1 2885/4885SMN1; SMN2 4883/4885
US-20080312319-A1 Modulation of Bacterial Quorum Sensing with Synthetic Ligands AHCYL1, EBPL, AIP LMNA 3895/4885ALDH1A1 2885/4885SMN1; SMN2 4883/4885
US-20150080349-A1 MODULATION OF BACTERIAL QUORUM SENSING WITH SYNTHETIC LIGANDS AHCYL1, EBPL, AIP LMNA 3895/4885ALDH1A1 2885/4885SMN1; SMN2 4883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.