SCHEMBL30920531

SCHEMBL30920531

COc1cc2c(cc1CO)cc(CNC(=O)C1(C)CC1)n2S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MTNR1B P49286 1/20 0.40
▸ PKM P14618 5/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ PPARG P37231 3/20 0.37
▸ PPARD Q03181 2/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ HTT P42858 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ PPARA Q07869 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ AGTR1 P30556 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27246728 1.00 MTNR1B (0.40) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL27247530 0.89 ALDH1A1 (0.41) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL27247431 0.89 MTNR1B (0.41) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL30920651 0.89 ALDH1A1 (0.41) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL30920502 0.89 MTNR1B (0.41) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL27247942 0.88 MTNR1B (0.46) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL30920244 0.87 MTNR1B (0.40) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL27247326 0.87 MTNR1B (0.40) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL30920440 0.87 MTNR1B (0.40) MTNR1BPKMMEN1KMT2APPARG
SCHEMBL27247593 0.87 MTNR1B (0.40) MTNR1BPKMMEN1KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
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