SCHEMBL30920630

SCHEMBL30920630

COc1cc2c(cc1C(C)C)cc(CNC(=O)OC(C)(C)C)n2S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MTNR1B P49286 1/20 0.40
▸ CYP2D6 P10635 1/20 0.39
▸ PPARG P37231 4/20 0.37
▸ PPARD Q03181 2/20 0.37
▸ TRPV1 Q8NER1 1/20 0.37
▸ PPARA Q07869 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ TSHR P16473 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ PKM P14618 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ POLB P06746 2/20 0.34
▸ KDM4A O75164 1/20 0.34
▸ NOD2 Q9HC29 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27247669 0.89 MTNR1B (0.46) MTNR1BPPARGPPARDPPARAKDM4E
SCHEMBL30920197 0.88 MTNR1B (0.41) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920412 0.87 MTNR1B (0.41) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920598 0.87 MTNR1B (0.42) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920221 0.87 CYP2D6 (0.41) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920806 0.86 MTNR1B (0.40) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920919 0.86 CYP2D6 (0.41) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920593 0.85 MTNR1B (0.40) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920703 0.84 TRPV1 (0.39) MTNR1BCYP2D6PPARGPPARDTRPV1
SCHEMBL30920244 0.83 MTNR1B (0.40) MTNR1BPPARGPPARDPPARAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601635-A2 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF Maze Therapeutics, Inc. (US) 2025-08-20 — — EP disclosed
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF HERCULES CAPITAL, INC., AS AGENT 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199546-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF SLC6A19, SLC2A9, SLC6A3 MTNR1B 111/4885CYP2D6 752/4885PPARG 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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