Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086593 | 0.85 | LCK (0.30) | LCKFYN | |
| SCHEMBL4665653 | 0.78 | CUL4A (0.39) | CUL4AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4907153 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL3089100 | 0.76 | CUL4A (0.38) | CUL4AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3092091 | 0.71 | HSD17B2 (0.40) | CUL4AKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL3084659 | 0.71 | BRD4 (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12804666 | 0.69 | ALDH1A1 (0.44) | KDM4EHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL3087985 | 0.69 | HPGD (0.42) | KDM4EHSD17B10HPGDALDH1A1MAPT | |
| SCHEMBL16372082 | 0.68 | HSD17B2 (0.47) | CUL4AKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL16372098 | 0.66 | CUL4A (0.39) | CUL4AKDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144879-B1 | PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION | BAYER IP GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |