Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924059 | 0.88 | EPHX2 (0.56) | P2RX7KCNH2MCHR1ACKR3EPHX2 | |
| SCHEMBL30924073 | 0.87 | CHRM4 (0.59) | P2RX7ALDH1A1CHRM4ACKR3 | |
| SCHEMBL30924081 | 0.86 | EPHX2 (0.51) | KCNH2MCHR1CHRM4EPHX2 | |
| SCHEMBL30924141 | 0.85 | ERCC1 (0.60) | P2RX7KCNH2MCHR1CHRM4EPHX2 | |
| SCHEMBL30923926 | 0.84 | CHRM2 (0.49) | CHRM4EPHX2 | |
| SCHEMBL30924146 | 0.83 | ACKR3 (0.53) | P2RX7ALDH1A1CHRM4ACKR3EPHX2 | |
| SCHEMBL30924119 | 0.79 | P2RX7 (0.52) | P2RX7ALDH1A1CHRM4ACKR3EPHX2 | |
| SCHEMBL30924061 | 0.79 | KCNH2 (0.54) | KCNH2MCHR1ACKR3EPHX2 | |
| SCHEMBL30924153 | 0.77 | P2RX7 (0.58) | P2RX7ALDH1A1EPHX2CYP2D6PKM | |
| SCHEMBL30924045 | 0.76 | ACKR3 (0.62) | KCNH2MCHR1ACKR3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |