Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924073 | 0.91 | CHRM4 (0.59) | P2RX7CHRM4ALDH1A1ACKR3 | |
| SCHEMBL30924124 | 0.88 | EPHX2 (0.63) | P2RX7EPHX2ACKR3 | |
| SCHEMBL30924006 | 0.86 | EPHX2 (0.55) | HTR2ACHRM4EPHX2 | |
| SCHEMBL30924120 | 0.83 | CHRM2 (0.53) | HTR2ACHRM4EPHX2 | |
| SCHEMBL30924141 | 0.81 | ERCC1 (0.60) | P2RX7CHRM4EPHX2 | |
| SCHEMBL30924038 | 0.79 | P2RX7 (0.48) | P2RX7CHRM4EPHX2ALDH1A1ACKR3 | |
| SCHEMBL30924146 | 0.79 | ACKR3 (0.53) | P2RX7CHRM4EPHX2ALDH1A1ACKR3 | |
| SCHEMBL30924153 | 0.79 | P2RX7 (0.58) | P2RX7EPHX2ALDH1A1 | |
| SCHEMBL30924136 | 0.78 | SIGMAR1 (0.67) | P2RX7EPHX2ACKR3 | |
| SCHEMBL12685848 | 0.77 | CHRM4 (0.67) | CHRM4ALDH1A1ACKR3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |