Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924119 | 0.91 | P2RX7 (0.52) | CHRM4ALDH1A1ACKR3P2RX7 | |
| SCHEMBL30924141 | 0.90 | ERCC1 (0.60) | CHRM4CHRM2P2RX7 | |
| SCHEMBL30924146 | 0.87 | ACKR3 (0.53) | CHRM4ALDH1A1ACKR3CHRM2P2RX7 | |
| SCHEMBL30924038 | 0.87 | P2RX7 (0.48) | CHRM4ALDH1A1ACKR3P2RX7 | |
| SCHEMBL30924136 | 0.87 | SIGMAR1 (0.67) | ACKR3P2RX7 | |
| SCHEMBL30924103 | 0.86 | CHRM4 (0.59) | CHRM4CHRM2 | |
| SCHEMBL12685848 | 0.86 | CHRM4 (0.67) | CHRM4ALDH1A1ACKR3 | |
| SCHEMBL30924102 | 0.85 | ACKR3 (0.58) | ALDH1A1ACKR3P2RX7 | |
| SCHEMBL30924104 | 0.84 | CHRM2 (0.62) | CHRM4CHRM2 | |
| SCHEMBL30924135 | 0.82 | BCHE (0.61) | CHRM4ALDH1A1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |