Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924099 | 0.87 | ACKR3 (0.57) | ACKR3SIGMAR1CHRM2ALDH1A1CACNA1G | |
| SCHEMBL30924154 | 0.86 | KDM4E (0.58) | SIGMAR1CHRM2ALDH1A1CACNA1GCHRM4 | |
| SCHEMBL30924130 | 0.80 | CHRM4 (0.61) | ACKR3CHRM2CHRM1CHRM4 | |
| SCHEMBL30924105 | 0.80 | P2RX7 (0.68) | ACKR3SIGMAR1 | |
| SCHEMBL30924112 | 0.80 | EPHX2 (0.77) | SIGMAR1CHRM4 | |
| SCHEMBL30924111 | 0.79 | CHRM4 (0.61) | SIGMAR1CHRM2CHRM1CHRM4 | |
| SCHEMBL23832299 | 0.78 | ACHE (0.67) | SIGMAR1 | |
| SCHEMBL30924093 | 0.77 | CACNA1G (0.58) | SIGMAR1CHRM2CACNA1GCHRM4 | |
| SCHEMBL30924083 | 0.77 | ACKR3 (0.62) | ACKR3SIGMAR1ALDH1A1 | |
| SCHEMBL30924123 | 0.77 | CHRM2 (0.59) | ACKR3CHRM2CHRM1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618985-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | Universitat De Barcelona (ES) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105234-A1 | DUAL INHIBITORS OF SIGMA-1 RECEPTOR AND SOLUBLE EPOXIDE HYDROLASE AND THEIR USE IN THE TREATMENT OF PAIN | UNIVERSITAT DE BARCELONA (ES) | 2024-05-23 | — | — | WO | disclosed |