Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668635 | 0.87 | IDO1 (0.55) | IDO1NPC1RAB9ASMN1; SMN2HTR2A | |
| SCHEMBL3339491 | 0.84 | FAAH (0.50) | IDO1TDP1CES1FAAHL3MBTL1 | |
| SCHEMBL13325994 | 0.84 | FAAH (0.50) | IDO1TDP1CES1FAAHL3MBTL1 | |
| SCHEMBL28563732 | 0.83 | CES1 (0.42) | CA1CA2CA9IDO1NPC1 | |
| SCHEMBL8376179 | 0.81 | CA1 (0.47) | CA1CA2CA9IDO1NPC1 | |
| SCHEMBL24213899 | 0.78 | TAAR1 (0.45) | CA1CA2IDO1CYP2A6HTR2A | |
| SCHEMBL28840110 | 0.77 | CA1 (0.44) | CA1CA2CA9IDO1NPC1 | |
| SCHEMBL2590168 | 0.77 | CA1 (0.44) | CA1CA2CA9IDO1NPC1 | |
| SCHEMBL22346842 | 0.77 | TSHR (0.54) | CA1IDO1TDP1SMN1; SMN2CES1 | |
| SCHEMBL21078946 | 0.77 | ALDH1A1 (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106399398-B | Biological preparation method of (R) -3, 5-bis (trifluoromethyl) phenethyl alcohol | 上海医药工业研究院 | 2024-07-09 | — | — | CN | claimed |
| CN-107418980-B | Clean production method of R-3, 5-bis (trifluoromethyl) phenethyl alcohol | 义乌市欣邦生物科技有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-104230667-B | The preparation of R-3,5-bis trifluoromethyl phenylethyl alcohol | WANG JIKUAN (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-103232324-B | The preparation method of a kind of (R)-3,5-pairs of (trifluoromethyl) phenylethyl alcohols | GUANGXI XINJING SCI. & TECH. CO., LTD. (CN) | 2016-03-16 | — | — | CN | claimed |
| CN-105330517-A | Method for synthesizing 3,5-bis(trifluoromethyl) phenethyl alcohol | ENANTIOTECH CORP LTD | 2016-02-17 | — | — | CN | claimed |
| CN-104230667-A | Preparation method of R-3, 5-bis (trifluoromethyl) phenyl ethanol | WANG JIKUAN | 2014-12-24 | — | — | CN | claimed |
| CN-101698633-A | Method for preparing trifluoromethyl benzyl alcohol by Grignard reaction | UNIV JIANGSU POLYTECHNIC | 2010-04-28 | — | — | CN | claimed |
| CN-106399398-B | Biological preparation method of (R) -3, 5-bis (trifluoromethyl) phenethyl alcohol | 上海医药工业研究院 | 2024-07-09 | — | — | CN | disclosed |
| CN-106399398-B | Biological preparation method of (R) -3, 5-bis (trifluoromethyl) phenethyl alcohol | 上海医药工业研究院 | 2024-07-09 | — | — | CN | disclosed |
| CN-117778341-A | Immobilized carbonyl reductase based on protein tag self-assembly and application of immobilized carbonyl reductase in continuous catalysis preparation of aprepitant intermediate | 浙江工业大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114774379-A | Carbonyl reductase mutant with improved thermal stability | 中国科学院成都生物研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-113801872-A | Method for preparing stable zymoprotein ring by accurate regulation and assembly | 杭州师范大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-112500517-A | Oil-soluble super-heavy oil viscosity reducer and preparation method and application thereof | 山东德仕化工有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-101781162-A | Method for preparing trifluoromethyl styrene compound | SHANGHAI CHEMEXPLORER CO LTD | 2010-07-21 | — | — | CN | disclosed |
| CN-101698633-A | Method for preparing trifluoromethyl benzyl alcohol by Grignard reaction | UNIV JIANGSU POLYTECHNIC | 2010-04-28 | — | — | CN | disclosed |
| CN-101636377-A | Benzylamines, processes for their preparation and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AG | 2010-01-27 | — | — | CN | disclosed |
| CN-100582093-C | Hydroisoindoline tachykinin receptor antagonists | MERCK & CO INC | 2010-01-20 | — | — | CN | disclosed |
| CN-1914171-A | Hydroisoindoline tachykinin receptor antagonists | MERCK & CO INC (US) | 2007-02-14 | — | — | CN | disclosed |
| CN-1242983-C | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2006-02-22 | — | — | CN | disclosed |
| CN-1308603-A | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2001-08-15 | — | — | CN | disclosed |