Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325994 | 1.00 | FAAH (0.50) | FAAHCES1SIGMAR1IDO1MAOA | |
| SCHEMBL9668635 | 0.92 | IDO1 (0.55) | FAAHCES1SIGMAR1IDO1MAOA | |
| SCHEMBL3092432 | 0.84 | CA1 (0.44) | FAAHCES1IDO1TDP1L3MBTL1 | |
| SCHEMBL3335357 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAA | |
| SCHEMBL816968 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAA | |
| SCHEMBL22282162 | 0.78 | IDO1 (0.48) | SIGMAR1IDO1MAOATDP1L3MBTL1 | |
| SCHEMBL11516805 | 0.77 | SIGMAR1 (0.56) | SIGMAR1IDO1MAOATDP1L3MBTL1 | |
| SCHEMBL7449055 | 0.77 | TDP1 (0.61) | SIGMAR1IDO1MAOATDP1L3MBTL1 | |
| SCHEMBL7449325 | 0.77 | TDP1 (0.61) | SIGMAR1IDO1MAOATDP1L3MBTL1 | |
| SCHEMBL7448881 | 0.77 | TDP1 (0.61) | SIGMAR1IDO1MAOATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152081-A1 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152081-A1 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100152081-A1 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2035131-A2 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003446-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008003446-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152081-A1 | Fluorosurfactants | CBR3, FPR3, NOX3 | FAAH 1225/4885CES1 1576/4885SIGMAR1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.