Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 8/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651158 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL21100434 | 0.88 | MGLL (0.33) | MGLLFAAH | |
| SCHEMBL17776326 | 0.88 | MGLL (0.33) | MGLLFAAH | |
| SCHEMBL19658181 | 0.86 | MGLL (0.33) | MGLL | |
| SCHEMBL18751704 | 0.86 | MGLL (0.33) | MGLL | |
| SCHEMBL19658322 | 0.86 | MGLL (0.33) | MGLL | |
| SCHEMBL15326761 | 0.81 | ALDH1A1 (0.35) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL13198303 | 0.79 | MGLL (0.30) | MGLL | |
| SCHEMBL26382053 | 0.79 | MGLL (0.30) | MGLL | |
| SCHEMBL871247 | 0.79 | MGLL (0.32) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024084390-A1 | COMPOUNDS FOR THE ACTIVATION OF AMPK | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |